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KMID : 0377619870520010025
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Korean Jungang Medical Journal
1987 Volume.52 No. 1 p.25 ~ p.33
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Spirit Healing (IV)
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Abstract
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The effects of temporary clipping on the arterial endothelium in rats were examined with electron microscopy. Twenty four rats were anesthetized and right common carotid arteries were exposed.
Temporary clips were used to occlude the carotid arteries for 5, 30, and 60 minutes in 6 animals each. The clips were then removed and blood flow resumed for periods of 0 and 30 minutes, respectively.
The TEM examination of the endothelium subjected to ischemia by acute occlusion revealed numerous intracytoplasmic vacuoles and alteration of organelles. Interendothelial junctions were frequently disrupted, and focal areas of endothelial cell desquamation with cleavage between endothelial cells and the underlying internal elastic lamina were also seen.
All of these alterations were detected in arterial segments that had been compressed for as little as 30 minutes. Similar alterations were observed in segments that had been compressed for 30 minutes followed by removal of the clip and resumption of blood flow for 30 minutes. However, the adherence of platelets and fibrin to altered endothelial cells and to exposed subendothelial tissue was markedly increased following resumption of blood flow for 30 minutes.
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